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Unwilling to hide his HIV+ status, entertainment reporter Karl Schmid came out to broad acclaim this year. We talk with the red carpet host about his career, deciding to disclose, and what's next on his rise to the top. PLUS: Our Annual HIV Treatment Guide looks at the most commonly prescribed HIV medications, newly approved drugs, treatments coming down the pipeline, and talking to your doc. Meanwhile, model and athlete Jack Mackenroth bares his soul (and more).

Annointed fashion's mysterious go-to designer, Viktor Luna took a step outside of his own closet, coming out as HIV-positive on Project Runway All-Stars. After the media blitz ensued, Luna stepped back from the limelight, for a calmer life in California — and some serious fashion lines in 2016 and 2017. Now he's joining a campaign to combat HIV stigma and talks about finding his own perfect work-life balance. Plus: Our annual special section: Just Diagnosed? We offer dozens of things you need to know in the days and months after learning you are now living with HIV.

Beloved fashion designer and reality star Viktor Luna knows what it’s like coming out poz on television. Now he’s taking it a step further.

Riveting portraits of ordinary lives of people living with HIV populate this issue.

Born with HIV, Ashley Rose Murphy has been an activist since she was in elementary school. She fought mild cerebral palsy, Fetal Alcohol Syndrome, and a learning disability — as well as HIV stigma — to become a kickass 19-year-old activist, a long-term survivor, and a Elizabeth Glaser Pediatric AIDS Foundation ambassador. Meanwhile, Poz diplomat Michael Varga was given months to live (in the 1990s). Instead, the former State Department employee continues to thrive.  Plus: Experts offer 15 things you need to know about HIV & aging.

On the front cover, Transparent's breakout stars, actresses Alexandra Billings and Trace Lysette, talk about living with HIV onscreen (and, for Alexandra, offscreen) as well as sexual harassment in Hollywood and being a transgender woman in America. And on the bonus special back cover, Broadway and MTV star Todrick Hall talks to us about getting black gay and bi men (and the world at large) to confront the epidemic rates of HIV in their future if nothing changes. Plus: We kick off Plus magazine's 20th anniversary with the 20 Amazing HIV+ People for 2018.

Amazon’s hit series broke all of Hollywood’s rules. Now, two of its stars are changing America’s perspective on women living with HIV.