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Protease Inhibitors



Generic name: nelfinavir


ViiV Healthcare

What it does:
Helps prevent replication of HIV

Traditional dosage:
1,250 mg (five 250 mg tablets or two 625 mg tablets), twice daily; or 750 milligrams (three 250 mg tablets), three times daily. Each dose should be taken with a meal. An oral powder is also available.

Drug interactions, precautions, & recommendations:
Do not take with Cordarone, Orap, Quinidine, Quinaglute, Cardioquin, Quinidex, D.H.E. 45 Injection, Ergomar, Migranal, Wigraine, Cafergot, Methergine, Halcion, Versed, Revatio (if used for pulmonary arterial hypertension), Uroxatral, Prilosec, Rimactane, Rifadin, Rifater, Rifamate, St. John’s Wort, Mevacor, Zocor, or Serevent. Use caution with Seroquel, Lipitor, Crestor, Pravachol, Lescol, Viagra, Levitra, Cialis, Adcirca, or Tracleer. If also taking Videx, take Viracept with food one hour after or more than two hours before Videx. May reduce effectiveness of birth control pills, so use alternative forms of contraception. Doses of Crixivan, Norvir, Invirase, Fortovase, Mycobutin or Dilantin may need to be adjusted. Rescriptor may lower the amount of Viracept in the blood or vice versa. Do not take if you have moderate to severe liver impairment.

Side effects:
Most serious: diabetes and high blood sugar, high blood pressure, changes in body fat or immune system

Other: diarrhea, nausea, rash

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