![Woman_dna_2](https://www.hivplusmag.com/media-library/woman-dna-2.jpg?id=32669749&width=1200&height=1200)
Treatment GuideJust DiagnosedSex & DatingAfrican AmericanStigmaAsk the HIV DocPrEP En EspañolNewsVoicesPrint IssueVideoOut 100
CONTACTCAREER OPPORTUNITIESADVERTISE WITH USPRIVACY POLICYPRIVACY PREFERENCESTERMS OF USELEGAL NOTICE
© 2024 Pride Publishing Inc.
All Rights reserved
All Rights reserved
By continuing to use our site, you agree to our Private Policy and Terms of Use.
Although no major medications are expected to hit the market in the next few months, the drug pipeline does contain a handful of candidates that are reaching the research stage of final clinical trials. ENTRY INHIBITORS [Medication Name/Code (with Drug Class), Research Stage, Manufacturer] ' DP-178 (fusion inhibitor), Preclinical, Weizmann Institute ' GP41 inhibitor, Preclinical, Locus Pharmaceuticals ' GSK706769 (CCR5 blocker), Phase I, GlaxoSmithKline ' IC9564 (BA entry inhibitor), Preclinical, Duke University ' INCB15050 (CCR5 blocker), Phase I, Incyte ' MDX-010 (CTLA-4 blocker), Preclinical, Medarex ' PF232798 (CCR5 blocker), Phase II, Pfizer ' PRO-140 (monoclonal antibody), Phase II, Progenics ' Sifuvirtide (fusion inhibitor), Phase IIb, FusoGen ' TBR-220 (CCR5 blocker), Phase I, Tobira ' TBR-652 (CCR5 blocker), Phase I, Tobira ' Ibalizumab TNX-355 (monoclonal antibody), Phase II, Taimed ' TRI-1144 (fusion inhibitor), Preclinical, Trimeris and Roche ' Vicriviroc (CCR5 blocker), Phase III, Schering-Plough ' Zinc finger protein nucleases (CCR5 blockers), Preclinical, Sangamo Biosciences -------------------- INTEGRASE INHIBITORS [Medication Name/Code, Research Stage, Manufacturer] ' Beta-diketo acids, Preclinical, University of Parma and University of Sassari ' Elvitegravir (GS-9137), Phase III, Gilead Sciences ' GS-9224, Preclinical, Gilead Sciences ' GSK364735, Phase I, GlaxoSmithKline/Shionogi ' GSK13495172, Phase II, GlaxoSmithKline -------------------- MATURATION INHIBITORS [Medication Name/Code, Research Stage, Manufacturer] ' Betulinic acid derivatives, Preclinical, University of North Carolina, Duke University, Vanderbilt University ' Bevirimat (gag processing inhibitor), Phase II, Myriad ' Capsid inhibitors, Preclinical, Achillion ' MPC 9055, Phase II, Myriad ' PA1050040, (gag processing inhibitor), Phase I, Panacos ' RPI-MN, (nAchR receptor inhibitor), Preclinical, ReceptoPharm -------------------- NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS [Medication Name/Code, Research Stage, Manufacturer] ' C-8 quinolinyloxyethyl substitutent, Preclinical, Boehringer Ingelheim ' HBY097 (Pyridinone derivatives), Preclinical, Rutgers University ' IDX899, Phase II, Idenix/GSK ' MV026048, Preclinical, Medivir ' Oligodeoxynucleotides, Preclinical, University of Zurich ' Rilpivirine (TMC-278), Phase III, Tibotec ' RDEA806, Phase IIa, Ardea ' RDEA427, Phase I, Ardea ' RDEA640, Preclinical, Ardea ' Thiazole derivatives, Preclinical, Japan's Institute for Virus Research ' UK-435061, Phase II, Pfizer -------------------- NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS [Medication Name/Code, Research Stage, Manufacturer] ' 4-Ed4T, Preclinical, Kagoshima University ' Amdoxovir (DAPD), Phase II, RFS Pharma ' Apricitabine (ATC), Phase IIb/III, Avexa ' Dexelvucitabine (DFC, formerly Reverset), Phase II, Pharmasset ' DOT (dioxolane thymidine), Phase I, University of Georgia ' Elvucitabine (ACH-126), Phase II, Achillion ' Fosalvudine (alovudine prodrug), Phase II, Heidelberg Pharmaceuticals ' GS-9131, Preclinical, Gilead Sciences ' GS-9148, Preclinical, Gilead Sciences ' IDX12899, Preclinical, Idenix Pharmaceuticals ' IDX12989, Preclinical, Idenix Pharmaceuticals ' Quinolones, Preclinical, Rega Institute ' Racivir, Phase II, Pharmasset ' Thiovir, Preclinical, Adventrx ' TSAO-T derivatives, Preclinical, University of Pittsburgh -------------------- PK BOOSTERS [Medication Name/Code, Research Stage, Manufacturer] ' GS-9350, Phase I, Gilead Sciences ' SPI-452, Phase I, Sequoia ' TMC558445, Phase I, Tibotec Pharmaceuticals ' PF-03716539, Phase I, Pfizer -------------------- PROTEASE INHIBITORS [Medication Name/Code, Research Stage, Manufacturer] ' GRL-02031, Preclinical, Kumamoto University ' SPI-256, Phase I, Sequoia -------------------- OTHER CLASSES [Medication Name/Code (with Drug Class), Research Stage, Manufacturer] ' 1H4 (tat inhibitor), Preclinical, Taras Shevchenko University ' BIT225 (Vpu ion blockers), Phase 1, Biotron Limited ' Histone deacetylase inhibitors, Phase I/II, University of California, San Francisco ' HRG214 (caprine IgG), Preclinical, Vironex ' KP-1461 (viral decay accelerator), Phase II, Koronis ' LEDGF (integrase competers), Preclinical, Catholic University of Leuven ' Poly acrylic acid, Preclinical, Chinese Academy of Science ' RSC-1838, Preclinical, GlaxoSmithKline and Shionogi ' SCY-635 (cyclophilin inhibitor), Phase Ib, Scynexis ' siRNA constructs (rev/tat inhibitors), Preclinical, Beckman Institute ' siRNA, Preclinical, CombiMatrix
Want more breaking equality news & trending entertainment stories?
Check out our NEW 24/7 streaming service: the Advocate Channel!
Download the Advocate Channel App for your mobile phone and your favorite streaming device!
From our Sponsors
Most Popular
Before AIDS, gay artist Rex drew hot men on the prowl — then he disappeared
April 11 2024 3:15 PM
Diets that mimic fasting reverse aging: study
March 07 2024 5:28 PM
PrEP without a prescription now a reality in California
February 06 2024 8:37 PM
Injectable HIV treatment, prevention: Everything you need to know
March 26 2024 3:28 PM
8 dating tips for gay men from a gay therapist
March 21 2024 2:50 PM
Happy national foreskin day!
April 04 2024 1:45 PM
The science behind U=U has been liberating people with HIV for years
June 04 2024 3:31 PM
Scarlet fever: exploring our fascination with blood
March 13 2024 1:47 PM
On Anal Sex Day, crack up with The Bottom's Digest
April 18 2024 10:22 AM
Plus: Featured Video
Latest Stories
Activist and philanthropist Bruce Bastian dies at 76
June 26 2024 1:28 PM
Yes, HIV-positive people can safely breastfeed
June 26 2024 12:59 PM
Exclusive: We kiki with Q from 'RuPaul's Drag Race'
June 24 2024 11:37 AM
Court rules to keep PrEP coverage under Obamacare
June 21 2024 5:42 PM
In honor of Juneteenth 2024, meet The Normal Anomaly
June 19 2024 1:39 PM
What is Juneteenth?
June 19 2024 11:30 AM
As Pride party season begins, the CDC urges mpox vaccinations
May 16 2024 6:52 PM
Advocacy in action with AIDSWatch
May 09 2024 12:30 PM
The Talk: Thriving with HIV
May 08 2024 10:45 AM
The Talk: What HIV isn’t
May 07 2024 10:48 AM
The Talk: Finding balance with HIV
May 06 2024 10:51 AM
Justice Dept plans to reschedule marijuana as a lower-risk drug
May 03 2024 2:40 PM
The Talk: Starting your journey with HIV
May 03 2024 2:00 PM
Why is a mother’s mental health so important? A doctor explains
May 01 2024 1:38 PM
Walmart to close all of its health care clinics
April 30 2024 12:30 PM
Vampire facial spa infected several women with HIV
April 29 2024 7:26 PM