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Kids' Responses to Meds Vary by Age

Kids' Responses to Meds Vary by Age


Immulogical responses to highly active antiretroviral therapy in children varies with age'with younger children the most likely to post larger CD4-cell increases but also being more likely to maintain higher viral loads, according to a study in the September 24 edition of the journal AIDS. CD4-cell percentage increases of more than 10% after six months of antiretroviral therapy were shown to be more common in younger children and in those starting therapy with the lowest CD4-cell percentages, researchers report. Suppressing HIV viral levels to below 400 copies, however, was most likely in older children, and was shown to be unrelated to pre-HAART viral levels or CD4-cell counts. Because higher viral levels are often a sign of the development of drug-resistance, the reseachers say younger HIV-positive children may be at a higher risk for treatment failure and faster HIV disease progression than older HIV-positive kids.

30 Years of Out100Out / Advocate Magazine - Jonathan Groff and Wayne Brady

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