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Combination Drugs

Atripla

Atripla

Generic names: efavirenz, emtricitabine, and tenofovir disoproxil fumarate

Atripla

Maker:
Gilead Sciences

What it does:
Helps prevent replication of HIV

Traditional dosage:
One tablet, once daily on an empty stomach, preferably at bedtime (600 mg of efavirenz, 200 mg emtricitabine, and 300 mg of tenofovir disoproxil fumarate). Efavirenz is an NNRTI, the other components NRTIs.

Drug interactions, precautions, & recommendations:
Do not take with medicines that contain lamivudine (Epivir, Epivir-HBV, Epzicom, Combivir, Trizivir), other HIV antiretroviral medications, drugs to treat seizures or tuberculosis, adefovir (Hespera), St John’s Wort, sofosbuvir/velpatasvir (Epclusa), or more than one dose of dexamethasone. Use caution with antidepressants, antifungals, antimalarials, birth control, blood thinner (warfarin), high blood pressure medication (calcium channel blockers), and methadone. If taken with Harvoni, you should be monitored.

Side effects:
Most serious:

buildup of lactic acid in blood, severe liver problems, kidney damage, hepatitis B flare-up, depression, bone thinning, changes in immune system

Other: dizziness, headache, trouble sleeping, drowsiness, trouble concentrating, abnormal dreams, rash

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Editor

Ryan is the Digital Director of The Advocate Channel, and a graduate of NYU Tisch's Department of Dramatic Writing. She is also a member of GALECA, the LGBTQ+ society of entertainment critics. While her specialties are television writing and comedy, Ryan is a young member of the LGBTQ+ community passionate about politics and advocating for all.

Ryan is the Digital Director of The Advocate Channel, and a graduate of NYU Tisch's Department of Dramatic Writing. She is also a member of GALECA, the LGBTQ+ society of entertainment critics. While her specialties are television writing and comedy, Ryan is a young member of the LGBTQ+ community passionate about politics and advocating for all.