Scroll To Top
Combination Drugs



Generic names: efavirenz, emtricitabine, and tenofovir disoproxil fumarate


Gilead Sciences

What it does:
Helps prevent replication of HIV

Traditional dosage:
One tablet, once daily on an empty stomach, preferably at bedtime (600 mg of efavirenz, 200 mg emtricitabine, and 300 mg of tenofovir disoproxil fumarate). Efavirenz is an NNRTI, the other components NRTIs.

Drug interactions, precautions, & recommendations:
Do not take with medicines that contain lamivudine (Epivir, Epivir-HBV, Epzicom, Combivir, Trizivir), other HIV antiretroviral medications, drugs to treat seizures or tuberculosis, adefovir (Hespera), St John’s Wort, sofosbuvir/velpatasvir (Epclusa), or more than one dose of dexamethasone. Use caution with antidepressants, antifungals, antimalarials, birth control, blood thinner (warfarin), high blood pressure medication (calcium channel blockers), and methadone. If taken with Harvoni, you should be monitored.

Side effects:
Most serious:

buildup of lactic acid in blood, severe liver problems, kidney damage, hepatitis B flare-up, depression, bone thinning, changes in immune system

Other: dizziness, headache, trouble sleeping, drowsiness, trouble concentrating, abnormal dreams, rash

Out Subscription Lil Nas XAdvocateChannel promotion

From our Sponsors

Most Popular

Fifth Person Cured of HIV

Be sure to follow Plus on your favorite social platforms!


Want more news, top stories, and videos? Check out the all NEW Advocate Channel!
Your 24/7 streaming source for equality news and lifestyle trends.
Click this link right now:

Latest Stories