What it does:
Helps prevent replication of HIV
One tablet, once daily on an empty stomach, preferably at bedtime (600 mg of efavirenz, 200 mg emtricitabine, and 300 mg of tenofovir disoproxil fumarate). Efavirenz is an NNRTI, the other components NRTIs.
Drug interactions, precautions, & recommendations:
Do not take with medicines that contain lamivudine (Epivir, Epivir-HBV, Epzicom, Combivir, Trizivir), other HIV antiretroviral medications, drugs to treat seizures or tuberculosis, adefovir (Hespera), St John’s Wort, sofosbuvir/velpatasvir (Epclusa), or more than one dose of dexamethasone. Use caution with antidepressants, antifungals, antimalarials, birth control, blood thinner (warfarin), high blood pressure medication (calcium channel blockers), and methadone. If taken with Harvoni, you should be monitored.
buildup of lactic acid in blood, severe liver problems, kidney damage, hepatitis B flare-up, depression, bone thinning, changes in immune system
Other: dizziness, headache, trouble sleeping, drowsiness, trouble concentrating, abnormal dreams, rash