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Generic name: efavirenz


Bristol-Myers Squibb

What it does:
Helps prevent replication of HIV

Traditional dosage:
600 mg (three capsules at once or one tablet), taken daily. Take Sustiva on an empty stomach, preferably at bedtime, with water.

Drug interactions, precautions, & recommendations:
Do not take with other NNRTIs, Atripla, Vascor, Propulsid, Versed, Orap, Halcion, Victrelis, Olysio; ergot medications (like Wigraine, Cafergot); Mepron or Paludrine. The following medicines may need to be replaced with others while taking Sustiva: Fortovase, Invirase, Biaxin, Carbatrol, Tegretol, Noxafil, Sporanox, and Reyataz. Change in doseage may be required of either Sustiva or these medicines: Cardizem, Tiazac, Covera HS, Isoptin SR, Lipitor, Pravachol, Zocor, Crixivan, Kaletra, methadone, Mycobutin, Reyataz, Rifadin, Rifamate, Rifater, Selzentry, Vfend, Gengraf, Neoral, Sandimmune, Prograf, Rapamune, Wellbutrin, Zoloft, and Zyvan. If taking Sustiva and Reyataz, you should also be taking Norvir. Tell your doctor if you have had hepatitis or other liver problems, mental illness, or seizures.

Side effects:
Most serious: severe liver problems, rashes, skin reactions
Other: changes in immune system or body fat, dizziness, nausea, headache, insomnia, tiredness

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