Traditional dosage: One tablet, containing 300 mg of abacavir sulfate, 150 mg of lamivudine, and 300 mg of zidovudine (all NRTIs), twice daily.
Drug interactions, precautions, & recommendations: Do not take if you have certain liver problems or weigh less than 90 pounds. Take with caution if you have the gene variation HLA-B*5701, hepatitis B, kidney or heart problems, low blood cell counts, high blood pressure, high cholesterol, or diabetes. Use with caution if you take Bactrim, Septra, Cytovene, DHPG, interferon-alfa (Pegasys, PegIntron), Adriamycin, Copegus, Rebetol, Virazole, Atripla, Combivir, Complera, Emtriva, Epivir or Epivir-HBV, Epzicom, Retrovir, Truvada, Zerit, Ziagen, or bone marrow suppressive or cytotoxic medicines.
Side effects: Most serious: severe or fatal allergic reactions, heart attack, buildup of lactic acid, liver disorders, blood problems, muscle weakness, body fat or immune system changes, hepatitis B flare-up Other: nausea, vomiting, headache, weakness, diarrhea, fever or chills, depression, muscle and joint pain, skin rashes, cold symptoms, nervousness, ear, nose, and throat infections