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Opportunistic Infections & Other Drugs

AmBisome, Amphotec, Abelcet, Amphocin,

AmBisome, Amphotec, Abelcet, Amphocin,

Generic name: amphotericin B

Astellas, Alkopharma, Sigma-Tau, Pfizer

What it does:
Treats fungal infections, including cryptococcal meningitis, which are more common in people with HIV

Traditional dosage:
No more than 1.5 mg per kg of body weight, administered intravenously, once daily

Drug interactions, precautions, & recommendations:
Individuals who cannot normally take traditional amphotericin B because it causes damage to their kidneys may be able to take the formulations in AmBisome, Abelcet, or Amphotec.

Side effects:
Most serious: allergic reaction, kidney problems, rash, irregular heartbeat, muscle cramps or pain, weakness, bleeding, hearing loss, blurred vision, hepatitis Other: fever, shaking, chills, weight loss, nausea, headache, jaundice
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