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Combination therapy and successful use of prophylaxis meds have dramatically slashed the incidence of most AIDS-related opportunistic infections since the beginning of the pandemic. But a few OIs remain serious concerns for HIVers, even for people on effective antiretroviral treatment, according to a study in the journal Clinical Infectious Diseases.Severe Risk (a sevenfold increased risk of death) > non-Hodgkin's lymphoma > progressive multifocal leukoencephalopathy Moderate Risk (more than double increased risk of death) > cryptococcosis > cerebral toxoplasmosis > AIDS dementia complex > disseminated mycobacterium avium complex
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