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Starting antiretroviral therapy earlier than recommended under current guidelines may not only improve long-term HIV disease control, as has been shown in previous studies, but also may reduce the risk of non-HIV-related cancers. Dutch researchers reviewed clinical data from nearly 11,500 HIVers and found the longer a person's CD4 cells remained below 350, the higher their risks of eventually developing non-AIDS-related cancers, particularly lung, anal, and other epithelial malignancies.