Treatment GuideJust DiagnosedSex & DatingAfrican AmericanStigmaAsk the HIV DocPrEP En EspañolNewsVoicesPrint IssueVideoOut 100
CONTACTCAREER OPPORTUNITIESADVERTISE WITH USPRIVACY POLICYPRIVACY PREFERENCESTERMS OF USELEGAL NOTICE
© 2024 Pride Publishing Inc.
All Rights reserved
All Rights reserved
By continuing to use our site, you agree to our Private Policy and Terms of Use.
New research suggests that many of the drug-resistant strains of HIV that have evolved over the past decade in San Francisco are more transmissible than had been thought. And experts predict that within the next five years these strains are likely to cause a new wave of virus that's highly resistant to medications, potentially proving disastrous by hindering control of the pandemic. In a study published January 14 on the website of the journal Science, researchers from the Semel Institute for Neuroscience and Human Behavior at the University of California, Los Angeles, and the University of California, San Francisco's HIV AIDS Program at San Francisco General Hospital developed a mathematical model that tracks the transmission of multiple strains of HIV. The model can be used to predict drug resistance in any setting where individuals are treated for HIV infection. While in this case it was applied to San Francisco, the researchers found that the drug-resistant strains emerging in that city are also very likely to emerge in many African countries where treatment is just beginning. "This isn't just about San Francisco," says senior author Sally Blower, director of UCLA's Center for Biomedical Modeling and a member of the UCLA AIDS Institute. "It's basically about many other communities in resource-rich countries and has significant implications for global health. San Francisco is like the canary in the mine. In fact, the most significant implications of our work are for countries where treatment is just being rolled out." "What is very unsettling," Blower continues, "is that our modeling shows that the current strategy for HIV elimination that is being proposed by the World Health Organization could inadvertently make things worse and significantly increase levels of drug resistance in many African countries." The researchers studied the evolution of drug-resistant strains over the past 20 years and predicted their spread over the next five years, according to Robert Smith, who was a postdoctoral fellow in Blower's lab when the research was conducted. Surprisingly, he says, their analysis showed that HIV was becoming more than simply stronger in its resistance to medications. "What was very disturbing was we found that some of the drug-resistant strains were increasing," says Smith, now an assistant professor in the department of mathematics and statistics at the University of Ottawa. The model was able to explain this increase, according to Justin T. Okano, also a research associate in Blower's group. "What is going on in San Francisco is very complicated, but in a nutshell," he elaborates, "it is due to the bug, the drugs, and sex."
From our Sponsors
Most Popular
The science behind U=U has been liberating people with HIV for years
June 04 2024 3:31 PM
Why activist Raif Derrazi thinks his HIV diagnosis is a gift
September 17 2024 12:00 PM
How fitness coach Tyriek Taylor reclaims his power from HIV with self-commitment
September 19 2024 12:00 PM
Exclusive: We kiki with Q from 'RuPaul's Drag Race'
June 24 2024 11:37 AM
The freedom of disclosure: David Anzuelo's journey through HIV, art, and advocacy
August 02 2024 12:21 PM
Out100 Honoree Tony Valenzuela thanks queer and trans communities for support in his HIV journey
September 18 2024 12:00 PM
Activist and philanthropist Bruce Bastian dies at 76
June 26 2024 1:28 PM
Creator and host Karl Schmid fights HIV stigma with knowledge
September 12 2024 12:03 PM
Plus: Featured Video
Latest Stories
Climate change is disrupting access to HIV treatment
November 25 2024 11:05 AM
California confirms first case of even more deadly mpox strain
November 18 2024 3:02 PM
Post-election blues? Some advice from mental health experts
November 08 2024 12:36 PM
Check out our 2024 year-end issue!
October 28 2024 2:08 PM
Meet our Health Hero of the Year, Armonté Butler
October 21 2024 12:53 PM
AIDS/LifeCycle is ending after more than 30 years
October 17 2024 12:40 PM
Twice-yearly injectable lenacapavir, an HIV-prevention drug, reduces risk by 96%
October 15 2024 5:03 PM
Kentucky bans conversion therapy for youth as Gov. Andy Beshear signs 'monumental' order
September 18 2024 11:13 AM
Study finds use of puberty blockers safe and reversible, countering anti-trans accusations
September 11 2024 1:11 PM
Latinx health tips / Consejos de salud para latinos (in English & en espanol)
September 10 2024 4:29 PM
The Trevor Project receives $5M grant to support LGBTQ+ youth mental health in rural Midwest (exclusive)
September 03 2024 9:30 AM
Introducing 'Health PLUS Wellness': The Latinx Issue!
August 30 2024 3:06 PM
La ciencia detrás de U=U ha estado liberando a las personas con VIH durante años
August 23 2024 2:48 PM
Tratamiento y prevención del VIH por inyección: Todo lo que necesita saber
August 23 2024 2:41 PM
Sr. Gay World quiere asegurarse de que estés bien
August 23 2024 2:30 PM
Eureka is taking a break from competing on 'Drag Race' following 'CVTW' elimination
August 20 2024 12:21 PM
With a new case in Sweden, what is the new mpox outbreak and should you be concerned?
August 15 2024 4:48 PM
From ‘The Real World’ to real life: How Danny Roberts thrives with HIV
July 31 2024 5:23 PM