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Entry and Fusion Inhibitors



Generic name: Maraviroc


ViiV Healthcare

What it does:
This is yet another mechanism of inhibiting viral replication. Always taken with other anti-HIV medications.

Traditional dosage:
300 mg twice daily; or 150 mg twice daily if taken with potent CYP3A inhibitors; or 600 mg twice daily if taken with potent CYP3A inducers.

Drug interactions, precautions, & recommendations:
Do not take St. John’s Wort, Prezista, Kaletra, Reyataz, Sustiva, Atripla, which may affect the amount of Selzentry in the blood. Tell your doctor if you have a history of hepatitis B or C, have heart or kidney problems, or if you have low blood pressure or take medication to lower it.

Side effects:
Most serious: heart or liver disorders, lowered blood pressure when standing, increased risk of cancer and infections, changes in immune system, severe rash, allergic reaction leading to hepatotoxicity
ther: cough, fever, dizziness, headache, lowered blood pressure, nausea, bladder irritation, upper respiratory infection

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