Traditional dosage: 400 mg in enteric-coated capsules, once daily, for individuals weighing 132 pounds or more. 250 mg, once daily, for adults weighing less than 132 pounds. Take on an empty stomach, swallow capsules whole; do not chew, break, crush, or dissolve. A powder form may be mixed with water for children.
Drug interactions, precautions, & recommendations: Do not take with Lopurin or Zyloprim (used to treat gout and kidney stones), or hepatitis drugs (Copegus, Rebetol, RibaTab, Ribasphere). Use caution with methadone, ganciclovir, or any drugs that may cause toxicity to the pancreas or nervous system. If also taking Viread, reduce Videx EC dose.
Side effects: Most serious: pancreatitis, buildup of lactic acid in blood, liver disorders, vision problems, immune system or body fat changes, peripheral neuropathy Other: diarrhea, nausea, vomiting, headache, stomach pain, skin rash