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Integrase Inhibitors

Isentress

Isentress

Generic name: Raltegravir

Isentress

Maker:
Merck

What it does:
Blocks integrase, an enzyme HIV needs to reproduce itself. Always taken with other anti-HIV medications

Traditional dosage:
One 400 mg tablet, twice daily. Available in oral suspension or chewable tablet for children, with dosage varying by weight.

Drug interactions, precautions, & recommendations:
Do not take with antacids that contain aluminum or magnesium hydroxide. Tell your doctor if you take the tuberculosis medication rifampin, or if you have liver problems or phenylketonuria. If you miss a dose, skip the missed dose and go back to your regular schedule. Do not double your next dose.

Side effects:
Most serious: severe skin reactions and allergic reactions, liver problems, immune system changes
Other: headache, trouble sleeping, nausea, tiredness, weakness, stomach pain, dizziness, depression, suicidal thoughts and actions

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