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The Truth About IRIS

The Truth About IRIS


What you need to know about immune reconstitution inflammatory syndrome, or IRIS.

What is it?
IRIS is an inflammatory condition that typically becomes noticeable after a person goes on HIV therapy for the first time or when people restart their medications after taking a lengthy break.  
Who gets IRIS?
It is prevalent mainly among people with damaged immune systems, including but not limited to those who are HIV-positive. People with TB, rheumatoid arthritis, lupus, Graves’ disease, hepatitis B or C, Kaposi’s sarcoma, shingles, cytomegalovirus, or herpes are also prone to IRIS. 
What are the symptoms?
IRIS is represented by soreness, rashes, swollen lymph nodes, and skin lesions. It can also lead to changes in breathing, pneumonia, hepatitis, abscesses, and eye inflammation. These symptoms can show up on any part of the body, including internal organs or nerve fibers.
How can it be treated? 
The science behind IRIS is still being deciphered, but people experiencing IRIS usually continue their HIV medication unless the inflammation becomes life-threatening. From there, a doctor would prescribe nonsteroidal anti-inflammatory drugs or corticosteroids to reduce the inflammation.
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