Treatment GuideJust DiagnosedSex & DatingAfrican AmericanStigmaAsk the HIV DocPrEP En EspañolNewsVoicesPrint IssueVideoOut 100
CONTACTCAREER OPPORTUNITIESADVERTISE WITH USPRIVACY POLICYPRIVACY PREFERENCESTERMS OF USELEGAL NOTICE
© 2024 Pride Publishing Inc.
All Rights reserved
All Rights reserved
By continuing to use our site, you agree to our Private Policy and Terms of Use.
According to a study to be published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism, postmenopausal HIV-infected women have a high prevalence of low-bone-mineral density and high bone turnover placing them at high risk for future bone fractures.
[ WELLNESS WEDNESDAY ]
"As HIV-infected individuals live longer with potent antiretroviral therapy, metabolic complications such as low bone density and osteoporosis are increasingly recognized," says Michael Yin, MD, of Columbia University Medical Center in New York and lead author of the study. "Although numbers of HIV-infected postmenopausal women are increasing and postmenopausal women are at highest risk for osteoporotic fractures, few studies have evaluated skeletal status in this group. We hypothesized that postmenopausal women might be particularly vulnerable to the adverse effects of HIV infection or ART on the skeleton and our results indicate that this may indeed be the case.""HIV infection was independently associated with lower bone-mineral density after adjusting for body mass index and traditional osteoporosis risk factors," says Yin. "While the reason for HIV-associated bone loss remains unclear, it may be related to increased levels of cytokines [proteins produced by cells that aid communication between cells], direct effects of antiretrovirals on bone cells or hormonal/nutritional deficiencies that are common in HIV."
"Estrogen protects against the effect of cytokines on bone resorption," Yin adds. "Therefore, as HIV-positive women become estrogen-deficient during menopause, they may be at higher risk for accelerated bone loss and fracture."
From our Sponsors
Most Popular
Why activist Raif Derrazi thinks his HIV diagnosis is a gift
September 17 2024 12:00 PM
How fitness coach Tyriek Taylor reclaims his power from HIV with self-commitment
September 19 2024 12:00 PM
Exclusive: We kiki with Q from 'RuPaul's Drag Race'
June 24 2024 11:37 AM
Out100 Honoree Tony Valenzuela thanks queer and trans communities for support in his HIV journey
September 18 2024 12:00 PM
The freedom of disclosure: David Anzuelo's journey through HIV, art, and advocacy
August 02 2024 12:21 PM
Activist and philanthropist Bruce Bastian dies at 76
June 26 2024 1:28 PM
Creator and host Karl Schmid fights HIV stigma with knowledge
September 12 2024 12:03 PM
In honor of Juneteenth 2024, meet The Normal Anomaly
June 19 2024 1:39 PM
Plus: Featured Video
Latest Stories
Climate change is disrupting access to HIV treatment
November 25 2024 11:05 AM
California confirms first case of even more deadly mpox strain
November 18 2024 3:02 PM
Post-election blues? Some advice from mental health experts
November 08 2024 12:36 PM
Check out our 2024 year-end issue!
October 28 2024 2:08 PM
Meet our Health Hero of the Year, Armonté Butler
October 21 2024 12:53 PM
AIDS/LifeCycle is ending after more than 30 years
October 17 2024 12:40 PM
Twice-yearly injectable lenacapavir, an HIV-prevention drug, reduces risk by 96%
October 15 2024 5:03 PM
Kentucky bans conversion therapy for youth as Gov. Andy Beshear signs 'monumental' order
September 18 2024 11:13 AM
Study finds use of puberty blockers safe and reversible, countering anti-trans accusations
September 11 2024 1:11 PM
Latinx health tips / Consejos de salud para latinos (in English & en espanol)
September 10 2024 4:29 PM
The Trevor Project receives $5M grant to support LGBTQ+ youth mental health in rural Midwest (exclusive)
September 03 2024 9:30 AM
Introducing 'Health PLUS Wellness': The Latinx Issue!
August 30 2024 3:06 PM
La ciencia detrás de U=U ha estado liberando a las personas con VIH durante años
August 23 2024 2:48 PM
Tratamiento y prevención del VIH por inyección: Todo lo que necesita saber
August 23 2024 2:41 PM
Sr. Gay World quiere asegurarse de que estés bien
August 23 2024 2:30 PM
Eureka is taking a break from competing on 'Drag Race' following 'CVTW' elimination
August 20 2024 12:21 PM
With a new case in Sweden, what is the new mpox outbreak and should you be concerned?
August 15 2024 4:48 PM
From ‘The Real World’ to real life: How Danny Roberts thrives with HIV
July 31 2024 5:23 PM