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Generic name: peginterferon alfa-2B



What it does:
Treats chronic hepatitis C, alone or in combination with other drugs

Traditional dosage:
1.5 micrograms per kg of body weight, once weekly, by subcutaneous injection; other doses no longer being manufactured.

Drug interactions, precautions, & recommendations:
Use caution with drugs metabolized by CYP2C8/9 or CYP2D6. Monitor for toxicities when used with NRTIs. Do not take if you have Stevens-Johnson syndrome, autoimmune hepatitis, or certain other liver problems. Do not take if you are pregnant or plan to become pregnant. Use with caution if you have a history of psychiatric disorders.

Side effects:
Most serious: severe eye, heart, blood, liver, nerve, thyroid, or lung problems; pancreatitis, colitis, high blood sugar or diabetes; or allergic reaction
Other: flu-like symptoms, tiredness, appetite problems, headache, nausea, myalgia, anxiety or emotional irritability, skin reactions, thinning hair

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