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Protease Inhibitors



Generic name: atazanavir


Bristol-Myers Squibb

What it does:
Helps prevent replication of HIV

Traditional dosage: 300 mg, in capsule form, taken with 100 mg of Norvir, once daily, with food. For adults unable to tolerate Norvir: 400 mg of Reyataz with food. Take at the same time every day.


Drug interactions, precautions, & recommendations:
Do not take with Versed, Halcion, Cafergot, Migranal, D.H.E. 45, Methergine, other ergot medicines, Orap, Camptosar, Crixivan, Mevacor, Zocor, Uroxatral, Revatio, Rimactane, Rifadin, Rifater, Rifamate, St. John’s Wort, Viramune, Diskus, or Advair. Do not take Vfend or Victrelis if you are taking Reyataz and Norvir; and do not take Tegretol, Dilantin, or drugs containing phenobarbital with Reyataz alone. If you are taking Videx, Videx EC, or antacids, take Reyataz two hours before or one hour after those medicines. Use with caution if taking drugs for indigestion, heartburn, or ulcers; depression; allergies or asthma; abnormal heart rhythm; blood clots; cholesterol; erectile dysfunction; gout; and certain other conditions. If taking Reyataz with Norvir and also taking Lamictal, dosage of the latter may need to be adjusted.

Side effects:
Most serious: severe rash, yellowing of skin or eyes, diabetes, kidney stones, worsening liver disease, increased bleeding problems, gallbladder disorders, changes in body fat, immune system, or heart rhythm

Other: nausea, headache, stomach pain, vomiting, diarrhea, depression, fever, dizziness, trouble sleeping, muscle pain, numbness, tingling, or burning of hands or feet

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