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Treatment

The Future of HIV Treatment May be Injectable Medication

The Future of HIV Treatment May be Injectable Medication

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Will you someday ditch your pills for a weekly shot to treat HIV?

Soon it may be possible to treat HIV with a weekly injection instead of pills.

Biotech firm CytoDyn plans a Phase III study — the final test before seeking Food and Drug Administration approval — of PRO 140, the first self-injectable antibody to treat HIV. The 25-week trial will involve 300 HIV-positive patients.

If approved, PRO 140, which has already shown ability to suppress the virus, will compete with Selzentry (both target the same protein, CCR%, thus preventing the entry of HIV into T cells), but PRO 140 appears to be less toxic, with fewer side effects. A Phase IIb study documented a 98 percent success rate for the drug in viral suppression, and it has the potential to treat other disorders, including certain inflammatory diseases, autoimmunity, and cancer, according to CytoDyn. The company intends to submit its final application to the FDA in November 2016, with PRO 140 going on the market in 2017, if the Phase III results are positive.

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Trudy Ring

Editor

Trudy Ring is The Advocate’s senior politics editor and copy chief. She has been a reporter and editor for daily newspapers and LGBTQ+ weeklies/monthlies, trade magazines, and reference books. She is a political junkie who thinks even the wonkiest details are fascinating, and she always loves to see political candidates who are groundbreaking in some way. She enjoys writing about other topics as well, including religion (she’s interested in what people believe and why), literature, theater, and film. Trudy is a proud “old movie weirdo” and loves the Hollywood films of the 1930s and ’40s above all others. Other interests include classic rock music (Bruce Springsteen rules!) and history. Oh, and she was a Jeopardy! contestant back in 1998 and won two games. Not up there with Amy Schneider, but Trudy still takes pride in this achievement.
Trudy Ring is The Advocate’s senior politics editor and copy chief. She has been a reporter and editor for daily newspapers and LGBTQ+ weeklies/monthlies, trade magazines, and reference books. She is a political junkie who thinks even the wonkiest details are fascinating, and she always loves to see political candidates who are groundbreaking in some way. She enjoys writing about other topics as well, including religion (she’s interested in what people believe and why), literature, theater, and film. Trudy is a proud “old movie weirdo” and loves the Hollywood films of the 1930s and ’40s above all others. Other interests include classic rock music (Bruce Springsteen rules!) and history. Oh, and she was a Jeopardy! contestant back in 1998 and won two games. Not up there with Amy Schneider, but Trudy still takes pride in this achievement.
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