![Coverx60_172](https://www.hivplusmag.com/media-library/coverx60-172.jpg?id=32679783&width=1200&height=1600)
Treatment GuideJust DiagnosedSex & DatingAfrican AmericanStigmaAsk the HIV DocPrEP En EspañolNewsVoicesPrint IssueVideoOut 100
CONTACTCAREER OPPORTUNITIESADVERTISE WITH USPRIVACY POLICYPRIVACY PREFERENCESTERMS OF USELEGAL NOTICE
© 2024 Pride Publishing Inc.
All Rights reserved
All Rights reserved
By continuing to use our site, you agree to our Private Policy and Terms of Use.
The Food and Drug Administration was due by March 16 to have decided on the marketing application for Roche and Trimeris's experimental HIV entry inhibitor Fuzeon. (No information was available about the expected approval at press time.) Fuzeon is the first anti-HIV drug to be developed in the entry inhibitor class. The Department of Health and Human Services gave approval in January for OraSure Technologies to more widely distribute its OraQuick Rapid HIV-1 Antibody Test to more than 100,000 sites nationwide, including physicians' offices and HIV counseling centers. The test, which can provide results in about 20 minutes, was approved by the Food and Drug Administration in November. Two four-month studies show that Bio-Technology General Corp.'s anabolic steroid oxandrolone, when combined with exercise and proper nutrition, increases weight and lean body tissue in patients suffering from HIV- or cancer-related wasting. Pharmacia Corp. announced in January that it will allow generic-drug makers to manufacture cheap copies of its HIV nonnucleoside reverse transcriptase inhibitor Rescriptor to sell in 78 developing nations. Two new studies show that Agouron's protease inhibitor Viracept does not increase the risk of birth defects in infants of pregnant women who take the anti-HIV medication and that taking the drug with a moderate-calorie, low-fat meal or a high-calorie, high-fat meal results in blood levels of the drug three to five times higher than achieved when taking it without food. Meanwhile, Roche, the distributor of the drug outside the United States, announced in February that it will slash the cost of Viracept to 'no-profit' prices in sub-Saharan Africa and other poor nations. A year's supply will cost about $800 to $900. Boehringer Ingelheim announced in February the launch of two Phase III clinical trials of its experimental second-generation, nonpeptidic protease inhibitor tipranivir. The trials include 1,500 people at more than 280 sites worldwide. Vertex Pharmaceuticals and GlaxoSmithKline report that a human trial of their once- or twice-daily experimental protease inhibitor GW433908 shows the drug reduced blood-based virus to undetectable levels in 66% of patients previously untreated for HIV disease. A new study shows that Gilead Sciences' experimental nucleoside reverse transcriptase inhibitor Coviracil is effective in suppressing HIV to undetectable levels when taken as part of a once-daily, protease inhibitor'sparing regimen. Auxilium announced on February 4 the launch of Testim, a testosterone gel that can be used in hormone replacement therapy for HIV-positive men with low testosterone levels. Data from a 50-patient study of Tibotec's experimental protease inhibitor TMC114 show that the drug has significant antiviral activity in multiple protease inhibitor'experienced patients currently on failing drug regimens. Roche Pharmaceuticals and Trimeris report that preliminary data from a human trial of their experimental entry inhibitor T-1249 show the compound is effective in suppressing HIV resistant to Fuzeon, the companies' other experimental entry inhibitor. Kucera Pharmaceutical has announced that the company is developing a new synthetic molecule, called KPC-2, that was shown in early tests to prevent HIV replication. The company plans to seek FDA approval to begin clinical trials. Data from a Phase I trial of Indevus (formerly Interneuron) Pharmaceuticals' experimental vaginal microbicide gel PRO 2000 show that the compound is safe and was well tolerated by both sexually active HIV-negative women and HIV-positive, abstinent women. Data from a 96-week clinical trial show that treatment-naive patients taking Gilead Sciences' nucleotide reverse transcriptase inhibitor Viread experience less lipodystrophy and have lower elevations in fasting cholesterol and triglycerides than study subjects taking d4T.
Want more breaking equality news & trending entertainment stories?
Check out our NEW 24/7 streaming service: the Advocate Channel!
Download the Advocate Channel App for your mobile phone and your favorite streaming device!
From our Sponsors
Most Popular
Before AIDS, gay artist Rex drew hot men on the prowl — then he disappeared
April 11 2024 3:15 PM
Diets that mimic fasting reverse aging: study
March 07 2024 5:28 PM
PrEP without a prescription now a reality in California
February 06 2024 8:37 PM
Injectable HIV treatment, prevention: Everything you need to know
March 26 2024 3:28 PM
8 dating tips for gay men from a gay therapist
March 21 2024 2:50 PM
Happy national foreskin day!
April 04 2024 1:45 PM
The science behind U=U has been liberating people with HIV for years
June 04 2024 3:31 PM
Scarlet fever: exploring our fascination with blood
March 13 2024 1:47 PM
On Anal Sex Day, crack up with The Bottom's Digest
April 18 2024 10:22 AM
Plus: Featured Video
Latest Stories
Activist and philanthropist Bruce Bastian dies at 76
June 26 2024 1:28 PM
Yes, HIV-positive people can safely breastfeed
June 26 2024 12:59 PM
Exclusive: We kiki with Q from 'RuPaul's Drag Race'
June 24 2024 11:37 AM
Court rules to keep PrEP coverage under Obamacare
June 21 2024 5:42 PM
In honor of Juneteenth 2024, meet The Normal Anomaly
June 19 2024 1:39 PM
What is Juneteenth?
June 19 2024 11:30 AM
As Pride party season begins, the CDC urges mpox vaccinations
May 16 2024 6:52 PM
Advocacy in action with AIDSWatch
May 09 2024 12:30 PM
The Talk: Thriving with HIV
May 08 2024 10:45 AM
The Talk: What HIV isn’t
May 07 2024 10:48 AM
The Talk: Finding balance with HIV
May 06 2024 10:51 AM
Justice Dept plans to reschedule marijuana as a lower-risk drug
May 03 2024 2:40 PM
The Talk: Starting your journey with HIV
May 03 2024 2:00 PM
Why is a mother’s mental health so important? A doctor explains
May 01 2024 1:38 PM
Walmart to close all of its health care clinics
April 30 2024 12:30 PM
Vampire facial spa infected several women with HIV
April 29 2024 7:26 PM