Treatment GuideJust DiagnosedSex & DatingAfrican AmericanStigmaAsk the HIV DocPrEP En EspañolNewsVoicesPrint IssueVideoOut 100
CONTACTCAREER OPPORTUNITIESADVERTISE WITH USPRIVACY POLICYPRIVACY PREFERENCESTERMS OF USELEGAL NOTICE
© 2024 Pride Publishing Inc.
All Rights reserved
All Rights reserved
By continuing to use our site, you agree to our Private Policy and Terms of Use.
Why is it so hard to isolate and purify HIV? Why has no one been able to see, by electron microscopy, a single HIV particle in the blood of AIDS patients, even those who have a high viral load? Why does HIV seem to mutate with startling rapidity? AIDS researchers have not been able to come up with answers to these questions.
Human endogenous retroviruses might provide explanations that have been overlooked for 20 years, writes Etienne de Harven, MD, in the fall 2010 issue of the Journal of American Physicians and Surgeons. HERVs are present in all of us, and fragments of their DNA may be confused with HIV in the polymerase chain reaction tests used to estimate viral load, he says.
The beautiful photographs of HIV published in both lay and scientific journals are embellished with special effects from computerized image reconstruction, according to De Harven. Since they come from cell cultures, which are likely to be contaminated, the particles may be "elegant artifacts" rather than the exogenous virus a virus of external origin believed to cause AIDS, De Harven states.
About 8% of the human genome consists of sequences incorporated from retroviruses. When cells break down, DNA fragments are released into the circulation, including these viral sequences. Patients with clinical AIDS carry a large spectrum of infectious diseases, so a high level of circulating DNA is expected.
While some people may challenge the role of HIV in AIDS, or even its existence, they are obligated to explain the observations of clinicians and researchers. HERVs are, at a minimum, a confounding variable that needs to be investigated, De Harven notes.
Puzzles involving the interpretation of diagnostic tests for HIV, the epidemiology and transmission patterns of AIDS, and strategies for prevention and treatment cannot be solved without broadening AIDS research beyond the narrow confines accepted by people who follow conventional wisdom about HIV, De Harven believes. Alternate hypotheses need to be objectively assessed, and conclusions must be based on scientific evidence rather than consensus.
Want more breaking equality news & trending entertainment stories?
Check out our NEW 24/7 streaming service: the Advocate Channel!
Download the Advocate Channel App for your mobile phone and your favorite streaming device!
From our Sponsors
Most Popular
Diets that mimic fasting reverse aging: study
March 07 2024 5:28 PM
Before AIDS, gay artist Rex drew hot men on the prowl — then he disappeared
April 11 2024 3:15 PM
The Most Amazing HIV Allies & Advocates of 2023
November 03 2023 12:51 PM
PrEP without a prescription now a reality in California
February 06 2024 8:37 PM
This OnlyFans Star Is Trying to Raise $100K to Fight HIV
December 26 2023 3:05 PM
Injectable HIV treatment, prevention: Everything you need to know
March 26 2024 3:28 PM
The naked Black body takes center stage in this HIV campaign
January 03 2024 1:07 PM
8 dating tips for gay men from a gay therapist
March 21 2024 2:50 PM
Mr. Gay World wants to make sure you're OK
January 02 2024 4:56 PM
Plus: Featured Video
Latest Stories
Our May/June issue of Plus is here!
April 17 2024 12:00 PM
Giselle Byrd is taking center stage — and helping others do the same
April 10 2024 2:24 PM
Discover endless fun at The Pride Store: Games & electronics for all ages
April 09 2024 4:25 PM
Mean Girls' Daniel Franzese on playing an HIV+ character
April 09 2024 3:57 PM
HIV-positive Air Force, Navy servicemembers victorious in lawsuit
April 09 2024 3:02 PM
Unlocking a new level of beauty with Dr Botanicals' ethical skincare line
April 08 2024 3:40 PM
Unleash your wild side with The Pride Store’s beginner’s guide to kink
April 08 2024 3:35 PM
Why are mpox cases in the U.S. on the rise again?
April 08 2024 1:30 PM
Happy national foreskin day!
April 04 2024 1:45 PM
Adult entertainment icons Derek Kage & Cody Silver lead fight for free speech
April 03 2024 3:06 PM
LGBTQ+ patients twice as likely to face discrimination: survey
April 02 2024 4:57 PM
Spring into The Pride Store’s top new arrivals for April
April 02 2024 4:39 PM
Nashville PD Must Pay HIV-Positive Man Denied a Job
April 01 2024 6:22 PM
Common has a message on how to foster self-love
March 29 2024 7:33 PM
Listen to Dr. Levine: Take syphilis seriously
March 28 2024 6:40 PM
Breaking boundaries in gender-free fashion with Stuzo Clothing
March 27 2024 2:15 PM
Find your perfect fit with gender-inclusive fashion from The Pride Store
March 26 2024 2:16 PM